Human
in vitro
| Time | Dose | Dose Level |
|---|---|---|
| 8 hr | 2ng/mL | Low |
| 24 hr | 2ng/mL | Low |
| 8 hr | 10ng/mL | Middle |
| 24 hr | 10ng/mL | Middle |
| 8 hr | 50ng/mL | High |
| 24 hr | 50ng/mL | High |
Detail of TNFa
| Time | Dose | Dose Level |
|---|---|---|
| 8 hr | 2ng/mL | Low |
| 24 hr | 2ng/mL | Low |
| 8 hr | 10ng/mL | Middle |
| 24 hr | 10ng/mL | Middle |
| 8 hr | 50ng/mL | High |
| 24 hr | 50ng/mL | High |